Recombinant Human Neurexophilin-1/NXPH1 Protein (His Tag)

Specifications

Catalog number

PKSH032794-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Neurexophilin-1 (NXPH1) is a member of Neurexophilin family. NXPH1 consist of 271 amino acis. It contains a 21 amino acid signal peptide, 86 amino acid propeptide, and 164 amino acid mature protein. NXPH1 is expressed in subpopulations of neurons within the cerebral cortex, cerebellum and olfactory bulb that are thought to be inhibitory interneurons. In humans, NXPH2 and NXPH3 are most similar to NXPH1, sharing 84% and 64% aa identity within the mature region, respectively. By contrast, NXPH4 dost not bind a-neurexins. Genetic deletion of NXPH1 or NXPH3 produces no anatomical effect.

Abbreviation

Neurexophilin-1; NXPH1

Synonyms

NPH1; NXPH1; Neurexophilin-1

UniProt

P58417

Accession Number

P58417

Expression System

HEK293 Cells

Tag

C-His

Sequence

Ala22-Gly271

Field of Research

Neuroscience

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

29.7 kDa

Observed Molecular Weight

40-60 kDa

Species

Human