Recombinant Human NLGN4X Protein (His Tag)

Specifications

Catalog number

PKSH032797-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Neuroligin 4, X-Linked (NLGN4X) is a single-pass type I membrane protein that belongs to the type-B carboxylesterase/lipase family. NLGN4X is detected at higher levels in heart and at lower levels in the liver, skeletal muscle, and pancreas. NLGN4X is a putative neuronal cell surface protein involved in cell-cell-interactions. NLGN4X may act as splice site-specific ligands for β-neurexins. It has been shown that NLGN4X is involved in the formation and remodeling of central nervous system synapses. NLGN4X also interacts with discs, large (Drosophila) homolog 4 (DLG4) . Defects in NLGN4X have been associated with autism and Asperger syndrome.

Abbreviation

NLGN4X

Synonyms

HNLX; KIAA1260; NLGN4; NLGN4X; Neuroligin X; Neuroligin-4 X-Linked

UniProt

Q8N0W4

Accession Number

Q8N0W4

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gln42-Ser676

Field of Research

Neuroscience

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

72.5 kDa

Observed Molecular Weight

95 kDa

Species

Human