Recombinant Human CHRNB3 Protein (His Tag)

Specifications

Catalog number

PKSH032799-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Neuronal acetylcholine receptor subunit beta-3 (CHRNB3) is a cell membrane protein and belongs to the ligand-gated ion channel (TC 1.A.9) family. CHRNB3 seems to be composed of two different type of subunits: alpha and beta. The CHRNB3 are (hetero) pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of CHRNB3 are encoded by separate genes and have different primary structure. There are several subtypes of neuronal CHRNB3 that vary based on which homologous subunits are arranged around the central channel. They are classified as alpha-subunits if like muscle alpha-1, they have a pair of adjacent cysteines as part of the presumed acetylcholine binding site. Subunits lacking these cysteine residues are classified as beta-subunits.

Abbreviation

CHRNB3

Synonyms

Neuronal acetylcholine receptor subunit beta-3

UniProt

Q05901

Accession Number

Q05901

Expression System

HEK293 Cells

Tag

C-His

Sequence

Ile25-Leu232

Field of Research

Neuroscience

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

25.3 kDa

Observed Molecular Weight

30-40 kDa

Species

Human