Recombinant Human Neuroplastin/NPTN Protein (His Tag)

Specifications

Catalog number

PKSH032801-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Neuroplastin (NPTN) is a 52-57 kDa member of the Ig-superfamily. Neuroplastin likely serves as a cell adhesion molecule, and is widely expressed in multiple tissues. Human Neuroplastin is 282 amino acids that contions two Ig-like domains and a 38 aa cytoplasmic region. Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. Neuroplastin may also regulate neurite outgrowth by activating the FGFR1 signaling pathway. It may play a role in synaptic plasticity.

Abbreviation

Neuroplastin; NPTN

Synonyms

NPTN; Neuroplastin; SDFR1; SDR-1; SDR1; Stromal Cell-Derived Receptor 1

UniProt

Q9Y639

Accession Number

Q9Y639

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gln29-His220

Field of Research

Cancer; immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

22.7 kDa

Observed Molecular Weight

35-55 kDa

Species

Human