Recombinant Human NHP2/NOLA2 Protein (His Tag)

Specifications

Catalog number

PKSH032829-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

NHP2 belongs to the H/ACA snoRNPs gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been organized into 2 families: C/D and H/ACA. NHP2 forms a small ribonucleoprotein particle with GAR1 (NOLA1) . NHP2 is involved in a variety of aspects of rRNA processing and modification. NHP2 localizes to the dense fibrillar component of the nucleolus and in nuclear Cajal bodies. NHP2 may also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.

Abbreviation

NHP2; NOLA2

Synonyms

H/ACA ribonucleoprotein complex subunit 2; NHP2; NHP2P. ; NOLA2; Nucleolar protein family A member 2; snoRNP protein NHP2

UniProt

Q9NX24

Accession Number

Q9NX24

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Leu153

Field of Research

Epigenetics and nuclear signal

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

19.3 kDa

Observed Molecular Weight

22 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 1mM DTT, pH 8.0.

Species

Human