Recombinant Human Parathyroid Hormone/PTH Protein (1-84)

Specifications

Catalog number

PKSH032854-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This hormone is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney. Another hormone; parathyroid hormone-related protein; binds to the same receptor as parathyroid hormone and has major effects on development. Like most other protein hormones; parathyroid hormone is synthesized as a preprohormone. After intracellular processing; the mature hormone is packaged within the Golgi into secretory vesicles; the secreted into blood by exocytosis. Parathyroid hormone is secreted as a linear protein of 84 amino acids.

Abbreviation

PTH

Synonyms

PTH; PTH1; Parathormone; Parathyrin; Parathyroid Hormone

UniProt

P01270

Accession Number

P01270

Expression System

E.coli

Tag

None

Sequence

Ser32-Gln115

Field of Research

Signal Transduction

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

9.4 kDa

Observed Molecular Weight

14 kDa

Species

Human