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Product details

Recombinant Human PD-L1/B7-H1/CD274 Protein (Flag Tag)

Catalog number PKSH032870-01

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Price for PKSH032870-01

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Size / count 10 µg

Specifications

Catalog number
PKSH032870-01
Size / count
10 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
CD274; also known as B7-H1 or programmed death ligand 1 (PD-L1) ; is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. Programmed death-1 ligand-1 (PD-L1; CD274; B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1 (PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. By binding to PD1 on activated T-cells and B-cells; PD-L1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression. Accordingly; it leads to growth of immunogenic tumor growth by increasing apoptosis of antigen specific T cells and may contribute to immune evasion by cancers. PD-L1 thus is regarded as promising therapeutic target for human autoimmune disease and malignant cancers.
Abbreviation
PD-L1; B7-H1; CD274
Synonyms
B7 Homolog 1; B7-H1; B7H1; CD274; PD-L1; PDCD1 Ligand 1; PDCD1L1; PDCD1LG1; PDL1; Programmed Cell Death 1 Ligand 1; Programmed Death Ligand 1
UniProt
Q9NZQ7
Accession Number
Q9NZQ7
Expression System
HEK293 Cells
Tag
C-Flag
Sequence
Phe19-Thr 239
Field of Research
Cancer; immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
26.3 kDa
Observed Molecular Weight
35-40 kDa
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human PD-L1/B7-H1/CD274 Protein (Flag Tag)?

The catalog number for Recombinant Human PD-L1/B7-H1/CD274 Protein (Flag Tag) is PKSH032870.

What sizes are available for Recombinant Human PD-L1/B7-H1/CD274 Protein (Flag Tag)?

Recombinant Human PD-L1/B7-H1/CD274 Protein (Flag Tag) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human PD-L1/B7-H1/CD274 Protein (Flag Tag) come in?

Recombinant Human PD-L1/B7-H1/CD274 Protein (Flag Tag) is available in 2 different pack sizes.

Is Recombinant Human PD-L1/B7-H1/CD274 Protein (Flag Tag) in stock?

Recombinant Human PD-L1/B7-H1/CD274 Protein (Flag Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human PD-L1/B7-H1/CD274 Protein (Flag Tag)?

Recombinant Human PD-L1/B7-H1/CD274 Protein (Flag Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human PD-L1/B7-H1/CD274 Protein (Flag Tag)?

Estimated delivery time for Recombinant Human PD-L1/B7-H1/CD274 Protein (Flag Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human PD-L1/B7-H1/CD274 Protein (Flag Tag)?

The safety data sheet for Recombinant Human PD-L1/B7-H1/CD274 Protein (Flag Tag) is available here: https://789.bio/eb/5inPmL.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

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