Recombinant Human Peptidase D/PEPD Protein

Specifications

Catalog number

PKSH032873-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

PEPD belongs to the peptidase M24B family of Eukaryotic-type prolidase subfamily. PEPD is a cytosolic dipeptidase that hydrolyzes dipeptides with proline or hydroxyproline at the carboxy terminus. It is important in collagen metabolism because of the high levels of imino acids. Defects in PEPD are a cause of prolidase deficiency which is an autosomal recessive disorder associated with iminodipeptiduria.

Abbreviation

Peptidase D; PEPD

Synonyms

Imidodipeptidase; PEPD.; PRD; PeptidaseD; Prolinedipeptidase; Xaa-Pro dipeptidase

UniProt

P12955

Accession Number

AAH28295.1

Expression System

E.coli

Tag

None

Sequence

Ala2-Lys493

Field of Research

Signal Transduction; Cell biology; Cancer; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

54.5 kDa

Observed Molecular Weight

60 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 25 mM Tris-HCl, 100 mM Glycine, 10% Glycerol, pH 8.5.

Species

Human