Recombinant Human Periostin/OSF-2 Protein (His Tag)

Specifications

Catalog number

PKSH032880-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Osteoblast-Specific Factor OSF-2 (POSTN, Periostin, OSF-2) is a secreted, homodimeric protein that belongs to the periostin family of the FAS1 superfamily of molecules. Periostin is a disulfide linked 90kDa bone adhesion protein secreted by osteoblasts and osteoblast-like cell lines and the protein is an attachment agent for osteoblasts. It is a TGF-beta inducible molecule that serves as both an adhesion molecule and tumor suppressor. It is synthesized by smooth muscle cells, fibroblasts and osteoblasts, as well as in the periosteum and periodontal ligament. Periostin functions as a ligand for alpha-V/beta-3 and alpha-V/beta-5 integrins to support adhesion and migration of epithelial cells.

Abbreviation

Periostin; OSF-2

Synonyms

OSF-2; Osteoblast-specific factor 2; PDLPOSTN; PN; POSTN; Periostin; periostin

UniProt

Q15063

Accession Number

Q15063-2

Expression System

HEK293 Cells

Tag

C-His

Sequence

Asn22-Gln779

Field of Research

Signal Transduction; Tags & Cell Markers; Cardiovascular; Cancer

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

85.6 kDa

Observed Molecular Weight

85-90 kDa

Species

Human