Recombinant Human Peroxiredoxin 5/PRDX5 Protein (His Tag)

Specifications

Catalog number

PKSH032885-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Peroxisomes are essential organelles that participate in multiple important metabolic processes, including the β-oxidation of fatty acids, plasmalogen synthesis, and the metabolism of reactive oxygen species (ROS) . Peroxiredoxins is overexpressed in breast cancer tissues to a great extent suggesting that they has a proliferative effect and may be related to cancer development or progression. Peroxiredoxin 5 (PRDX5) is a thioredoxin peroxidase that belongs to the atypical 2-Cys class of the TSA/ahpC family of peroxiredoxins. PRDX5 is a widely expressed mitochondrial antioxidant enzyme that reduces hydrogen peroxide, alkyl hydroperoxides, and peroxynitrite. In human cells, this enzyme is present in the cytosol, mitochondria, peroxisomes, and nucleus.

Abbreviation

Peroxiredoxin 5; PRDX5

Synonyms

AOEB166; Alu corepressor 1; Antioxidant enzyme B166; Liver tissue 2D-page spot 71B; PLP; PRDX5; Peroxiredoxin V; Peroxiredoxin-5; Peroxisomal antioxidant enzyme; Prx-V; TPx type VI; Thioredoxin peroxidase PMP20; Thioredoxin reductase

UniProt

P30044

Accession Number

P30044

Expression System

HEK293 Cells

Tag

N-His

Sequence

Met53-Leu214

Field of Research

Cell biology; Cancer; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

17.9 kDa

Observed Molecular Weight

17 kDa

Species

Human