Recombinant Human Profilin-2/PFN2 Protein

Specifications

Catalog number

PKSH032935-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Profilin-II (PFN2) is ubiquitous protein which belongs to the profilin family. PFN2 binds to actin, thenaffects the structure of the cytoskeleton. At high concentrations, profiling prevents the polymerization of actin, while increases that at low concentrations. PFN2 is a ubiquitous actin monomer-binding protein. It regulates actin polymerization in response to extra cellular signals. PFN2 binds to PIP2; it inhibits the formation of IP3 and DG.

Abbreviation

Profilin-2; PFN2

Synonyms

PFL; PFN2; Profilin-2; Profilin-II

UniProt

P35080

Accession Number

P35080

Expression System

E.coli

Tag

None

Sequence

Met 1-Phe140

Field of Research

Signal Transduction; Tags & Cell Markers

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

15.0 kDa

Observed Molecular Weight

14 kDa

Species

Human