Recombinant Human Progonadoliberin-2/GNRH2 Protein (His Tag)

Specifications

Catalog number

PKSH032936-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Progonadoliberin-2, also known as Progonadoliberin II and GNRH2, belongs to the gonadotropin-releasing hormone family. GNRH2 is specially expressed in midbrain, at significantly higher levels outside the brain (up to 30-fold) . GNRH2 can be cleaved into two chains, gonadoliberin-2 and GnRH-associated peptide 2. gonadoliberin-2 regulates reproduction in females by stimulating the secretion of both luteinizing- and follicle-stimulating hormones. The proproteins produce three transcript variants, but produce the same peptide hormone.

Abbreviation

Progonadoliberin-2; GNRH2

Synonyms

GNRH2; GnRH II; GnRH-Associated Peptide 2; GnRH-Associated Peptide II; Gonadoliberin II; Gonadoliberin-2; Gonadotropin-Releasing Hormone II; LH-RH II; Luliberin II; Luteinizing Hormone-Releasing Hormone II; Progonadoliberin II; Progonadoliberin-2

UniProt

O43555

Accession Number

O43555

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gln24-Val120

Field of Research

Signal Transduction; Developmental Biology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

11.6 kDa

Observed Molecular Weight

14-25 kDa

Species

Human