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Product details

Recombinant Human PCSK9 Protein (D374Y, His Tag)

Q: What is the catalog number for Recombinant Human PCSK9 Protein (D374Y, His Tag)?

The catalog number for Recombinant Human PCSK9 Protein (D374Y, His Tag) is PKSH032947.

Q: What sizes are available for Recombinant Human PCSK9 Protein (D374Y, His Tag)?

Recombinant Human PCSK9 Protein (D374Y, His Tag) is available in the following size(s): 10 µg, 50 µg.

Q: How many pack sizes does Recombinant Human PCSK9 Protein (D374Y, His Tag) come in?

Recombinant Human PCSK9 Protein (D374Y, His Tag) is available in 2 different pack sizes.

Q: Is Recombinant Human PCSK9 Protein (D374Y, His Tag) in stock?

Recombinant Human PCSK9 Protein (D374Y, His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Q: Who manufactures Recombinant Human PCSK9 Protein (D374Y, His Tag)?

Recombinant Human PCSK9 Protein (D374Y, His Tag) is manufactured by Elabscience.

Q: What is the estimated delivery time for Recombinant Human PCSK9 Protein (D374Y, His Tag)?

Estimated delivery time for Recombinant Human PCSK9 Protein (D374Y, His Tag) is approximately 15 business day(s), depending on your location.

Q: Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human PCSK9 Protein (D374Y, His Tag)?

The safety data sheet for Recombinant Human PCSK9 Protein (D374Y, His Tag) is available here: https://789.bio/eb/8iPqnD.

Q: What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

Q: What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Q: Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

Catalog number PKSH032947-01

Choose a variant (2 options)

Selecting a variant updates its price, size and availability.

Price for PKSH032947-01

Size / count 10 µg

Specifications

Catalog number: PKSH032947-01
Size / count: 10 µg
Dry ice: No
Hazardous: No
Discontinued: No
Background: Recombinant Human Proprotein Convertase Subtilisin/Kexin Type 9/PCSK9 (D374Y) is a gain of function mutant of human PCSK9 protein. Human PCSK9 is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER, the pro domain and mature chain are secreted together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and it plays a major regulatory role in cholesterol homeostasis. Inhibition of PCSK9 function by preventing PCSK9/LDLR interaction is currently being explored as a means of lowering cholesterol levels. PCSK9 also binds to apolipoprotein receptor 2 (ApoER2), and play a role in the neural development.
Abbreviation: PCSK9
Synonyms: NARC-1; NARC1; Neural Apoptosis-Regulated Convertase 1; PC9; PCSK9; Proprotein Convertase 9; Proprotein Convertase Subtilisin/Kexin Type 9; Subtilisin/Kexin-Like Protease PC9
UniProt: Q8NBP7
Accession Number: Q8NBP7
Expression System: HEK293 Cells
Tag: C-His
Sequence: Gln31-Gln692 (Asp374Tyr, Val474Ile, Gly504Arg, Gly670Glu)
Applications: ELISA
Field of Research: Signal Transduction; Cell biology; Cardiovascular; Cancer; metabolism; Stem cells
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Purity: > 90 % as determined by reducing SDS-PAGE.
Bioactivity: 50
Reconstitution: Not Applicable
Shipping Conditions: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight: 15-18&60-80 kDa
Observed Molecular Weight: 13.8&58.2 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 20% Glycerol, pH 7.4.
Species: Human

Frequently Asked Questions

What is the catalog number for Recombinant Human PCSK9 Protein (D374Y, His Tag)?

The catalog number for Recombinant Human PCSK9 Protein (D374Y, His Tag) is PKSH032947.

What sizes are available for Recombinant Human PCSK9 Protein (D374Y, His Tag)?

Recombinant Human PCSK9 Protein (D374Y, His Tag) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human PCSK9 Protein (D374Y, His Tag) come in?

Recombinant Human PCSK9 Protein (D374Y, His Tag) is available in 2 different pack sizes.

Is Recombinant Human PCSK9 Protein (D374Y, His Tag) in stock?

Recombinant Human PCSK9 Protein (D374Y, His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human PCSK9 Protein (D374Y, His Tag)?

Recombinant Human PCSK9 Protein (D374Y, His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human PCSK9 Protein (D374Y, His Tag)?

Estimated delivery time for Recombinant Human PCSK9 Protein (D374Y, His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human PCSK9 Protein (D374Y, His Tag)?

The safety data sheet for Recombinant Human PCSK9 Protein (D374Y, His Tag) is available here: https://789.bio/eb/8iPqnD.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.