Recombinant Human FAM19A4 Protein (His Tag)

Specifications

Catalog number

PKSH032961-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

FAM19A4 is a secreted, 12 kDa member of the FAM19/TAFA family of chemokine-like proteins. Like other members of the FAM19/TAFA family, with the exception of TAFA5, mature FAM19A4 contains 10 regularly spaced cysteine residues. The FAM19A4 proteins are predominantly expressed in specific regions of the brain and the biological functions of FAM19A4 family members remain to be determined, but there are a few tentative hypotheses. First, FAM19A4 may modulate immune responses in the CNS by functioning as brain specific chemokines, and may act with other chemokines to optimize the recruitment and activity of immune cells in the CNS. Second, FAM19A4 may represent a novel class of neurokines that act as regulators of immune nervous cells. And third, FAM19A4 may control axonal sprouting following brain injury.

Abbreviation

FAM19A4

Synonyms

Chemokine-like protein TAFA-4; FAM19A4; Protein FAM19A4; TAFA4; chemokine-like protein TAFA-4; family with sequence similarity 19 (chemokine (C-C motif) -like) ; member A4

UniProt

Q96LR4

Accession Number

Q96LR4

Expression System

E.coli

Tag

N-His

Sequence

Ser35-Arg140

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

14.1 kDa

Observed Molecular Weight

16 kDa

Species

Human