Recombinant Human PPM1G/PP2C-gamma Protein (His Tag)

Specifications

Catalog number

PKSH032970-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Protein Phosphatase 1G (PP1MG) is a cytoplasmic protein that belongs to the PP2C family. PPM1G is widely expressed; it is abundant in testis; skeletal muscle; and heart. PPM1G is a negative regulator of cell stress response pathways. PPM1G is responsible for the dephosphorylation of Pre-mRNA splicing factors; an important factor for the formation of functional spliceosome. PPM1G also plays a role in regulating cell cycle progression.

Abbreviation

PPM1G; PP2C-gamma

Synonyms

PP2C-Gamma; PP2CG; PP2CGAMMA; PPM1G; Protein Phosphatase 1C; Protein Phosphatase 1G; Protein Phosphatase 2C Isoform Gamma; Protein Phosphatase Magnesium-Dependent 1 Gamma

UniProt

O15355

Accession Number

O15355

Expression System

E.coli

Tag

C-His

Sequence

Met317-Asp546

Field of Research

Signal Transduction; Cell biology; epigenetics and nuclear signal

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

26.2 kDa

Observed Molecular Weight

30 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 25mM Tris-HCl, 1mM DTT, 1mM EDTA, 2mM β-ME, 20% Glycerol, pH 7.5.

Species

Human