Recombinant Human SCO1/SCOD1 Protein (GST Tag)

Specifications

Catalog number

PKSH032971-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Protein SCO1 Homolog, Mitochondrial (SCO1) is a member of the SCO1/2 family. SCO1 has a homodimer structure. SCO1 is located in mitochondrion and is highly expressed in muscle, heart, and brain. It is characterized by high rates of Oxidative Phosphorylation (OxPhos) . SCO1 is thought to play a important role in cellular copper homeostasis, mitochondrial redox signaling and insertion of copper into the active site of COX. The defects of SCO1 can result in Mitochondrial Complex IV Deficiency (MT-C4D) . A disorder of the mitochondrial respiratory chain has heterogeneous clinical manifestations, ranging from isolated myopathy to severe multisystem disease affecting several tissues and organs.

Abbreviation

SCO1; SCOD1

Synonyms

Protein SCO1 Homolog Mitochondrial; SCO1; SCOD1

UniProt

O75880

Accession Number

O75880

Expression System

E.coli

Tag

N-GST

Sequence

Gly132-Ser301

Field of Research

Signal Transduction; Tags & Cell Markers; Cancer; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

20.1 kDa

Observed Molecular Weight

19 kDa

Species

Human