Recombinant Human Protocadherin-1/PCDH1 Protein (His Tag)

Specifications

Catalog number

PKSH032977-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Protocadherin-1, also known as Cadherin-like protein 1, Protocadherin-42 and PCDH1, belongs to the protocadherin subfamily within the cadherin superfamily. PCDH1 contains seven cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. PCDH1 can be detected as early as embryonic day 9.5. In early embryogenesis, expression is especially prominent in blood vessels. The tight spatial and temporal regulation of Pcdh1 expression suggests that this protocadherin plays multiple roles not only during development but also in mature tissues and organs. In addition, protocadherin-1 is involved in cell-cell interaction processes and in neural cell adhesion.

Abbreviation

Protocadherin-1; PCDH1

Synonyms

Cadherin-Like Protein 1; PC42; PCDH1; Protocadherin-1; Protocadherin-42

UniProt

Q08174

Accession Number

Q08174

Expression System

HEK293 Cells

Tag

C-His

Sequence

Thr58-Asn852

Field of Research

Signal Transduction; Neuroscience

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

87.3 kDa

Observed Molecular Weight

120 kDa

Species

Human