Recombinant Human Retinol-Binding Protein 1/RBP1 Protein

Specifications

Catalog number

PKSH032996-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Retinol-binding proteins (RBP) are a family of proteins with diverse functions. They are carrier proteins that bind retinol. Retinol and retinoic acid play crucial roles in the modulation of gene expression and overall development of an embryo. However, deficit or excess of either one of these substances can cause early embryo mortality or developmental malformations. Regulation of transport and metabolism of retinol necessary for a successful pregnancy is accomplished via RBP. Retinol binding proteins have been identified within the uterus, embryo, and extraembryonic tissue of the bovine, ovine, and porcine, clearly indicating that RBP plays a role in proper retinol exposure to the embryo and successful transport at the maternal-fetal interface.

Abbreviation

Retinol-Binding1; RBP1

Synonyms

CRBP; CRBP-I; CRBP1; Cellular retinol-binding protein; Cellular retinol-binding protein I; RBP1; Retinol-binding protein 1

UniProt

P09455

Accession Number

P09455

Expression System

E.coli

Tag

None

Sequence

Pro2-Gln135

Field of Research

Signal Transduction; epigenetics and nuclear signal

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

15.7 kDa

Observed Molecular Weight

14 kDa

Species

Human