Recombinant Human Ribonuclease K6/RNASE6 Protein (His Tag)

Specifications

Catalog number

PKSH033003-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Ribonuclease K6 (RNASE6) is a secreted protein that belongs to the pancreatic ribonuclease family. Human RNASE6 is synthesized as a 150 amino acid precursor that contains a 23 amino acid signal sequence, and a 127 amino acid mature chain. RNASE6 is expressed in many tissues, with high expression levels in the lung, with lower expression levels in the heart, placenta, kidney, pancreas, liver, brain, and skeletal muscle. It is also detected in monocytes and neutrophils. RNASE6 may have a role in host defense.

Abbreviation

Ribonuclease K6; RNASE6

Synonyms

RNASE6; RNS6; RNase K6; Ribonuclease K6

UniProt

Q93091

Accession Number

Q93091

Expression System

HEK293 Cells

Tag

C-His

Sequence

Trp24-Leu150

Field of Research

Epigenetics and nuclear signal

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

15.7 kDa

Observed Molecular Weight

18-25 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, 10% Glycerol, pH 7.5.

Species

Human