Recombinant Human Semaphorin 3C/SEMA3C Protein (His Tag)

Specifications

Catalog number

PKSH033017-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Semaphorin 3C is one of six Class 3 secreted semaphorins, which are potent chemorepellents, that play a role in axon and/or vascular guidance during development can be up-regulated in the process of tumor progression. Semaphorin 3C consists of a 20 amino acids signal sequence, a N-terminal Sema domain, a cysteine knot, a furine-type cleavage site, an Ig-like domain, and a C-terminal basic domain. Semaphorin 3C expressed highly in the heart, colon, skeletal muscle, small intestine, testis, ovary and prostate, expressed lowly in the other organs, including the brain.

Abbreviation

Semaphorin 3C; SEMA3C

Synonyms

SEMA3C; SEMAE; Sema E; Semaphorin-3C; Semaphorin-E

UniProt

Q99985

Accession Number

Q99985

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gly21-Ser738

Field of Research

Cardiovascular; Neuroscience

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

82.4 kDa

Observed Molecular Weight

75-120&27KD

Formulation

24

Species

Human