Recombinant Human SerpinA4/SERPINA4 Protein (His Tag)

Specifications

Catalog number

PKSH033033-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Serpin Peptidase Inhibitor, Clade A (α-1 Antiproteinase, Antitrypsin), Member 4 (Serpin A4) is a member of the Serpin family. Serpin A4 exists as a monomer and some homodimers. Serpin A4 is expressed by the liver and secreted in plasma. Serpin A4 is a regulator of vascular homeostasis capable of controlling a wide spectrum of biological actions in the cardiovascular and renal systems. It can inhibit intracellular reactive oxygen species formation in cultured cardiac and renal cells. In addition, Serpin A4 has anti-inflammatory effect. Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity.

Abbreviation

SerpinA4; SERPINA4

Synonyms

KST; Kallikrein Inhibitor; Kallistatin; PI-4; PI4; Peptidase Inhibitor 4; SERPINA4; Serpin A4

UniProt

P29622

Accession Number

P29622

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gln21-Pro427

Field of Research

Cell biology; Cardiovascular; Cancer

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

47.1 kDa

Observed Molecular Weight

60-80 KDa

Formulation

2

Species

Human