Recombinant Human SerpinB12/SERPINB12 Protein (His Tag)

Specifications

Catalog number

PKSH033037-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Serpin B12 is a member of the serpin family. Serpins are the largest and most diverse family of serine protease inhibitors. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids. Serpin B12 is expressed in many tissues, including brain, bone marrow, lymph node, heart, lung, liver, pancreas, testis, ovary, and intestine. Serpins are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. SerpinB12 inhibits trypsin and plasmin, but not thrombin, coagulation factor Xa, or urokinase-type plasminogen activator.

Abbreviation

SerpinB12; SERPINB12

Synonyms

SERPINB12; Serine Protease Inhibitor-clade B12; Serpin B12

UniProt

Q3SYB4

Accession Number

Q96P63-2

Expression System

HEK293 Cells

Tag

C-His

Sequence

Met 1-Pro425

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

49.5 kDa

Observed Molecular Weight

55 kDa

Species

Human