Recombinant Human Serum Amyloid A1/SAA1 Protein (His Tag)

Specifications

Catalog number

PKSH033049-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Serum Amyloid A1 Protein (SAA1) is an acute phase apolipoprotein reactant that is produced predominantly by hepatocytes and is under the regulation of inflammatory cytokines. SAA is produced mainly in the liver and circulates in low levels in the blood. SAA may play a role in the immune system and facilitate the repair of injured tissues, it also acts as an antibacterial agent, and signals the migration of germ-fighting cells to sites of infection. SAA also functions as an apolipoprotein of the HDL complex. The SAA cleavage product designated amyloid protein A is deposited systemically as amyloid in vital organs such as the liver, spleen, and kidneys in chronic inflammatory diseases patients. These deposits are extremely insoluble and resistant to proteolysis; they disrupt tissue structure and compromise performance.

Abbreviation

Serum Amyloid A1; SAA1

Synonyms

SAA; SAA1; Serum Amyloid A-1 Protein

UniProt

P0DJI8

Accession Number

AAH07022.1

Expression System

E.coli

Tag

N-His

Sequence

Arg19-Tyr122

Field of Research

Signal Transduction; Cardiovascular; immunology; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

13.2 kDa

Observed Molecular Weight

14 kDa

Species

Human