Recombinant Human SGTA Protein (His Tag)

Specifications

Catalog number

PKSH033051-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein α (SGTA) is an ubiquitously expressed protein which belongs to the SGT Family. SGTA contains three TPR Protein-Protein Interaction Duplicates. SGTA is a co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. SGTA is capable of interacting with the major nonstructural protein of Parvovirus H-1 and 70-kDa heat shock cognate protein. It interacts with NS1 from Parvovirus H-1, with Vpu and Gag from HIV-1. It also interacts with SARS-CoV Accessory Protein 7a, DNAJC5 and DNAJC5B. However, its function is not known. Since this transcript is expressed ubiquitously in various tissues, SGTA may serve a housekeeping function.

Abbreviation

SGTA

Synonyms

Alpha-SGT; SGT; SGT1; SGTA; Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein Alpha; UBP; Vpu-Binding Protein

UniProt

O43765

Accession Number

O43765

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Glu313

Field of Research

Signal Transduction; Cell biology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

36.2 kDa

Observed Molecular Weight

35 kDa

Species

Human