Recombinant Human SUMO3/SMT3A Protein (aa 2-92, His Tag)

Specifications

Catalog number

PKSH033069-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Small ubiquitin-like modifier (SUMO) ; also known as SUMO homologue and SMT3; is a member of the superfamily of ubiquitin-like polypeptides that become covalently attached to various intracellular target proteins as a way to alter their function; location; and/or half-life. Small ubiquitin-like modifiers include SUMO1; SUMO2; SUMO3; and SUMO4. Except for SUMO4; all other SUMOs are ubiquitously expressed; including in the brain. In human; SUMO2 and SUMO3 are two highly homologous proteins; collectively called SUMO2/3. Several studies suggest that SUMO3 are associated with pathogenesis in several neurological diseases; including Alzheimer's disease; Parkinson's disease; and cerebral ischemia/stroke.

Abbreviation

SUMO3; SMT3A

Synonyms

SMT3 homolog 1; SUMO-2; SUMO-3; Small ubiquitin-related modifier 3; Smt3A ; Ubiquitin-like protein SMT3A

UniProt

P55854

Accession Number

P55854

Expression System

HEK293 Cells

Tag

C-His

Sequence

Ser2-Gly92

Field of Research

Cell biology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

11.1 kDa

Observed Molecular Weight

20 kDa

Species

Human