Recombinant Human TRIM/TRAT1 Protein (His Tag)

Specifications

Catalog number

PKSH033097-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

T-Cell Receptor-Associated Transmembrane Adapter 1 (TRAT1) is a single-pass type III membrane protein. TRAT1 exists as a disulfide-linked homodimer and is strongly expressed in the thymus, and to a lesser extent in the spleen, lymph node, and peripheral blood lymphocytes. TRAT1 is phosphorylated on tyrosines by LCK or FYN upon TCR activation. Its function is to stabilizes the TCR (T-cell antigen receptor) /CD3 complex at the surface of T-cells.

Abbreviation

TRIM; TRAT1

Synonyms

HSPC062; T-Cell Receptor-Associated Transmembrane Adapter 1; T-Cell Receptor-Interacting Molecule; TCRIM; TRAT1; TRIM; pp29/30

UniProt

Q6PIZ9

Accession Number

Q6PIZ9

Expression System

E.coli

Tag

C-His

Sequence

Asn29-Asn186

Field of Research

Signal Transduction; immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

19.4 kDa

Observed Molecular Weight

30 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM EDTA, 20% Glycerol, pH8.0.

Species

Human