Recombinant Human Thioredoxin-2/TXN2 Protein

Specifications

Catalog number

PKSH033109-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Thioredoxin-2 (TXN2) is a mitochondrial member of the thioredoxin family. Thioredoxin-2 is extensively expressed in adult and fetal tissues. Thioredoxin-2 contains an N-terminal 59 amino acid transit peptide; which is cleaved before translocating to mitochondria. Mitochondrial thioredoxin play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. Thioredoxin-2 could be involved in the resistance to anti-tumor agents and possesses a dithiol-reducing activity. In addition; Thioredoxin-2 is important at low oxidative stress conditions.

Abbreviation

Thioredoxin-2; TXN2

Synonyms

MTRX; Mt-Trx; TRX2; TXN2; Thioredoxin Mitochondrial; Thioredoxin-2

UniProt

Q99757

Accession Number

Q99757

Expression System

E.coli

Tag

None

Sequence

Thr60-Gly166

Field of Research

Signal Transduction; Cancer; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

12.0 kDa

Observed Molecular Weight

13 kDa

Species

Human