Recombinant Human TREML2/TLT2 Protein (Fc Tag)

Specifications

Catalog number

PKSH033146-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Trem-like transcript 2 protein (TLT2), also known as Triggering receptor expressed on myeloid cells-like protein 2, TLT2 and C6orf76, is single-pass type I membrane protein. TREML2 contains one Ig-like V-type domain, which can be induced in CD4 T-cell by concanavalin-A. As a cell surface receptor, TREML2 may play a role in the innate and adaptive immune response. TREML2 also acts as a counter-receptor for CD276 and interaction with CD276 on T-cells enhances T-cell activation. It has shown that TREML2 may be involved in the innate immune response based on its expression profile and the fact that it is up-regulated in response to inflammation.

Abbreviation

TREML2; TLT2

Synonyms

C6orf76; TLT2; Trem-like transcript 2 protein; Triggering receptor expressed on myeloid cells-like protein 2

UniProt

Q5T2D2

Accession Number

AAI25079.1

Expression System

HEK293 Cells

Tag

C-Fc

Sequence

Gly19-Ser268

Field of Research

Immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

54.2 kDa

Observed Molecular Weight

80-110 kDa

Species

Human