Recombinant Human INPP5A Protein (His Tag)

Specifications

Catalog number

PKSH033170-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Type I inositol 1,4,5-trisphosphate 5-phosphatase is a 412 amino acids protein that belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family. Type I inositol-1,4,5-trisphosphate 5-phosphatase is an enzyme that in humans is encoded by the INPP5A gene. It is expressed in brain and high level in Purkinje cells. InsP3 5-phosphatases hydrolyze Ins (1,4,5) P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.

Abbreviation

INPP5A

Synonyms

INPP5A; Type I inositol 1,4,5-trisphosphate 5-phosphatase

UniProt

Q14642

Accession Number

Q14642

Expression System

HEK293 Cells

Tag

C-His

Sequence

Met 1-Val410

Field of Research

Signal Transduction

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

48.7 kDa

Observed Molecular Weight

45 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Species

Human