Recombinant Human UBE2D3 Protein

Specifications

Catalog number

PKSH033183-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

UBE2D3 is an enzyme that belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.

Abbreviation

UBE2D3

Synonyms

UBE2D3 and UBCH5C.; Ubiquitin carrier protein D3; Ubiquitin-conjugating enzyme E2 D3; Ubiquitin-conjugating enzyme E2 (17) KB 3; Ubiquitin-conjugating enzyme E2-17 kDa 3; Ubiquitin-protein ligase D3

UniProt

P61077

Accession Number

AAH66917

Expression System

E.coli

Tag

None

Sequence

Met 1-Met 147

Field of Research

Cell biology; epigenetics and nuclear signal

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

16.6 kDa

Observed Molecular Weight

15 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 8% Sucrose, 150mM NaCl, 50% Glycerol, 0.05% Tween 80, 1mM TCEP, pH7.1.

Species

Human