Recombinant Human UGRP1 Protein

Specifications

Catalog number

PKSH033201-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Uteroglobin-Related Protein 1 (UGRP1) belongs to the secretoglobin family which has been suggested to play a role in lung inflammation and allergic diseases. UGRP1 is a 17 kDa secreted homodimeric protein that shows amino acid sequence similarity with uteroglobin. UGRP1 is expressed predominantly in the lung and low levels of expression are detected in the thyroid. Expression of UGRP1 in lung epithelial cells is enhanced by IL-10 and decreased through the activities of IL-9 and IL-5. UGRP1 interacts with the macrophage scavenger receptor with collagenous structure which is expressed by alveolar macrophages in the lung. It have suggested that UGRP1 may be involved in inflammation and pathogen clearance in the lung by binding to its receptor.

Abbreviation

UGRP1

Synonyms

PNSP1; PnSP-1; Pneumo Secretory Protein 1; SCGB3A2; Secretoglobin Family 3A Member 2; UGRP1; Uteroglobin-Related Protein 1

UniProt

Q96PL1

Accession Number

Q96PL1

Expression System

E.coli

Tag

None

Sequence

Phe22-Val93

Field of Research

Epigenetics and nuclear signal

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

7.9 kDa

Observed Molecular Weight

6&7 kDa

Species

Human