Recombinant Human VEGF-D/VEGFD Protein (His Tag)

Specifications

Catalog number

PKSH033211-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Vascular endothelial growth factor D (VEGF-D) is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. It is highly expressed in lung, heart, small intestine and fetal lung, and at lower levels in skeletal muscle, colon, and pancreas. VEGF-D is growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. It may function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. It undergoes a complex proteolytic maturation, generating multiple processed forms that bind and activate VEGFR-2 and VEGFR-3 receptors.

Abbreviation

VEGF-D; VEGFD

Synonyms

FIGF; VEGF-D; VEGFD; Vascular Endothelial Growth Factor D; c-Fos-Induced Growth Factor

UniProt

O43915

Accession Number

O43915

Expression System

HEK293 Cells

Tag

C-His

Sequence

Phe93-Ser201

Field of Research

Signal Transduction; Cardiovascular; Cancer

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

13 kDa

Observed Molecular Weight

18 kDa

Species

Human