Recombinant Human Vitronectin/VTN Protein (His Tag)

Specifications

Catalog number

PKSH033218-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Human Vitronectin/VTN is a cell adhesion and spreading factor. It can be found in the blood and the extracellular matrix (ECM) . Vitronectin interacts with glycosaminoglycans and proteoglycans. The multimeric Vitronectin can efficiently bind to and incorporate into the ECM; Vitronectin can support cell adhesion through binding to various integrins and other proteoglycans. Vitronectin can be recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecular. It can as a inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. Vitronectin contains an endogenous cleavage site; plus cleavage sites for elastase; thrombin; and plasmin.

Abbreviation

Vitronectin; VTN

Synonyms

S-Protein; Serum-Spreading Factor; V75; VN; VTN; Vitronectin

UniProt

P04004

Accession Number

AAH05046.1

Expression System

HEK293 Cells

Tag

C-His

Sequence

Asp20-Leu478

Field of Research

Cardiovascular; immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

53.4 kDa

Observed Molecular Weight

60-80 kDa

Species

Human