Recombinant Human VSTM1 Protein (His Tag)

Specifications

Catalog number

PKSH033222-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

V-set and transmembrane domain-containing protein 1 is a single-pass membrane protein. VSTM1 Contains 1 Ig-like V-type domain, in humans is encoded by the VSTM1 gene. It expressed on myeloid (neutrophils, eosinophils and monocytes) but not on lymphoid cells. It behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17) . Inhibitory immune receptor involved in the regulation of phagocytes.

Abbreviation

VSTM1

Synonyms

SIRL-1; Signal inhibitory receptor on leukocytes-1; V-set and transmembrane domain-containing protein 1; VSTM1

UniProt

Q6UX27

Accession Number

Q6UX27

Expression System

HEK293 Cells

Tag

C-His

Sequence

Tyr17-Thr135

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

14.6 kDa

Observed Molecular Weight

25-35 kDa

Species

Human