Recombinant Human XPNPEP3 Protein (His Tag)

Specifications

Catalog number

PKSH033229-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Probable Xaa-Pro Aminopeptidase 3 (XPNPEP3) is a member of the peptidase M24B family. XPNPEP3 has two isoforms and both are widely expressed. XPNPEP3 is localized in the Mitochondrion. XPNPEP3 catalyzes the release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Defects in XPNPEP3 are the cause of nephronophthisis-like nephropathy type 1 which is a disorder with features of nephronophthisis, a cystic kidney disease leading to end-stage renal failure.

Abbreviation

XPNPEP3

Synonyms

APP3; Aminopeptidase P3; Probable Xaa-Pro Aminopeptidase 3; X-Pro Aminopeptidase 3; XPNPEP3

UniProt

Q9NQH7

Accession Number

Q9NQH7

Expression System

E.coli

Tag

N-His & C-His

Sequence

Met 1-Ser507

Field of Research

Signal Transduction; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

60.2 kDa

Observed Molecular Weight

65 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 25mM Tris, 1mM DTT, pH 7.3.

Species

Human