Recombinant Human ZAG/AZGP1 Protein (His Tag)

Specifications

Catalog number

PKSH033242-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Zinc-α-2-Glycoprotein (AZGP1) can be found in blood plasma; seminal plasma; urine; sweat; saliva; liver; and epithelial cells of various human glands. AZGP1 has been proposed in the regulation of body weight; and the melanin production by normal and malignant melanocytes. AZGP1 stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. AZGP1 has been reported to stimulate lipid breakdown and may have an important role in lipid homeostasis. Mature human AZGP1 consists of one MHC class I antigen region and a C2-type Ig-like domain. AZGP1 has two alternate splice forms; one shows a 66 amino acids substitution for the C-terminal 30 amino acids; the other one shows a nine Lys substitution for amino acid 151-298.

Abbreviation

ZAG; AZGP1

Synonyms

AZGP1; ZAG; ZNGP1; Zinc-Alpha-2-Glycoprotein; Zn-Alpha-2-GP; Zn-Alpha-2-Glycoprotein

UniProt

P25311

Accession Number

P25311

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gln21-Ser298

Field of Research

Signal Transduction; immunology; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

33.2 kDa

Observed Molecular Weight

42 kDa

Species

Human