Recombinant Human Alpha-Galactosidase A/GLA Protein (His Tag) — image 1 of 3

Product details

Recombinant Human Alpha-Galactosidase A/GLA Protein (His Tag)

Q: What is the catalog number for Recombinant Human Alpha-Galactosidase A/GLA Protein (His Tag)?

The catalog number for Recombinant Human Alpha-Galactosidase A/GLA Protein (His Tag) is PKSH033249.

Q: What is the estimated delivery time for Recombinant Human Alpha-Galactosidase A/GLA Protein (His Tag)?

Estimated delivery time for Recombinant Human Alpha-Galactosidase A/GLA Protein (His Tag) is approximately 15 business day(s), depending on your location.

Q: Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human Alpha-Galactosidase A/GLA Protein (His Tag)?

The safety data sheet for Recombinant Human Alpha-Galactosidase A/GLA Protein (His Tag) is available here: https://789.bio/eb/azPy9G.

Q: Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Q: Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

Q: How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Catalog number PKSH033249-01

Choose a variant (2 options)

Selecting a variant updates its price, size and availability.

Price for PKSH033249-01

Size / count 10 µg

Specifications

Catalog number: PKSH033249-01
Size / count: 10 µg
Dry ice: No
Hazardous: No
Discontinued: No
Background: Α-Galactosidase A is a homodimeric glycoprotein that belongs to the glycosyl hydrolase 27 family. It is a lysosomal enzyme and used as a long-term enzyme replacement therapy in patients with a confirmed diagnosis of Fabry disease. α-Galactosidase A can hydrolyze terminal α-galactosyl moieties from glycolipids and glycoproteins and catalyze the hydrolysis of melibiose into galactose and glucose. Defects α-Galactosidase A are the cause of Fabry disease (FD) which is a rare X-linked sphingolipidosis disease with glycolipid accumulates in many tissues. The disease consists of an inborn error of glycosphingolipid catabolism. FD patients show systemic accumulation of globotriaoslyceramide (Gb3) and related glycosphingolipids in the plasma and cellular lysosomes throughout the body. Patients may show ocular deposits, febrile episodes, and burning pain in the extremities. Death results from renal failure, cardiac or cerebral complications of hypertension or other vascular disease.
Abbreviation: Alpha-Galactosidase A; GLA
Synonyms: Agalsidase; Alpha-D-Galactosidase A; Alpha-D-Galactoside Galactohydrolase; Alpha-Galactosidase A; GLA; GLAL; Melibiase
UniProt: P06280
Accession Number: P06280
Expression System: HEK293 Cells
Tag: C-His
Sequence: Leu32-Leu429
Field of Research: Cardiovascular
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Purity: > 95 % as determined by reducing SDS-PAGE.
Bioactivity: Not validated for activity
Reconstitution: Not Applicable
Shipping Conditions: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight: 46.4 kDa
Observed Molecular Weight: 50-60 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Species: Human

Frequently Asked Questions

What is the catalog number for Recombinant Human Alpha-Galactosidase A/GLA Protein (His Tag)?

The catalog number for Recombinant Human Alpha-Galactosidase A/GLA Protein (His Tag) is PKSH033249.

What sizes are available for Recombinant Human Alpha-Galactosidase A/GLA Protein (His Tag)?

Recombinant Human Alpha-Galactosidase A/GLA Protein (His Tag) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human Alpha-Galactosidase A/GLA Protein (His Tag) come in?

Recombinant Human Alpha-Galactosidase A/GLA Protein (His Tag) is available in 2 different pack sizes.

Is Recombinant Human Alpha-Galactosidase A/GLA Protein (His Tag) in stock?

Recombinant Human Alpha-Galactosidase A/GLA Protein (His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human Alpha-Galactosidase A/GLA Protein (His Tag)?

Recombinant Human Alpha-Galactosidase A/GLA Protein (His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human Alpha-Galactosidase A/GLA Protein (His Tag)?

Estimated delivery time for Recombinant Human Alpha-Galactosidase A/GLA Protein (His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human Alpha-Galactosidase A/GLA Protein (His Tag)?

The safety data sheet for Recombinant Human Alpha-Galactosidase A/GLA Protein (His Tag) is available here: https://789.bio/eb/azPy9G.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.