Recombinant Human Alpha-Parvin/PARVA Protein (His Tag)

Specifications

Catalog number

PKSH033252-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Alpha-Parvin (PARVA) is a member of the Parvin family. PARVA contains two CH (calponin-homology) domains. PARVA is widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. PARVA interacts with integrin-linked protein kinase and probably with actin and the LD1 and LD4 motifs of PXN. PARVA may play a role in the regulation of cell adhesion and cytoskeleton organization. PARVA is also involved in ciliogenesis.

Abbreviation

Alpha-Parvin; PARVA

Synonyms

Actopaxin; Alpha-Parvin; CH-ILKBP; Calponin-Like Integrin-Linked Kinase-Binding Protein; MXRA2; Matrix-Remodeling-Associated Protein 2; PARVA

UniProt

Q9NVD7

Accession Number

Q9NVD7

Expression System

E.coli

Tag

C-His

Sequence

Met 1-Glu372

Field of Research

Signal Transduction

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 85 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

43.2 kDa

Observed Molecular Weight

50-62 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 50mM Tris, 150mM NaCl, 40% Glycerol, pH 7.4.

Species

Human