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Product details

Recombinant Human Beta-2-Microglobulin/B2M Protein (E.coli, His Tag)

Catalog number PKSH033260-01

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Price for PKSH033260-01

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Size / count 10 µg

Specifications

Catalog number
PKSH033260-01
Size / count
10 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
Β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M component of major histocompatibility complex (MHC) class I molecules; involved in the presentation of peptide antigens to the immune system. Polymers of beta 2-microglobulin can be found in tissues from patients on long-term hemodialysis. B2M is a protein found on the surface of many cells and plentiful on the surface of white blood cells. Serum B2M concentration is increased in renal diseases; various malignant diseases and some inflammatory and autoimmune disorders. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states. The capacity to assemble into amyloid fibrils is concentration dependent. B2M has been shown as a marker for monitoring inflammatory disease activity and it appears likely to have a destructive role in amyloidosis-related arthritis. B2M might be involved in the OA (osteoarthritis) pathogenesis. Defects in B2M are the cause of hypercatabolic hypoproteinemia. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin; probably due to rapid degradation. B2M could be a potential therapeutic target in ovarian cancer.
Abbreviation
Beta-2-Microglobulin; B2M
Synonyms
B2M; Beta-2-Microglobulin; β2-Microglobulin
UniProt
P61769
Accession Number
P61769
Expression System
E.coli
Tag
N-His
Sequence
Ile21-Met 119
Field of Research
Cardiovascular; Cancer
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
14.0 kDa
Observed Molecular Weight
14 kDa
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human Beta-2-Microglobulin/B2M Protein (E.coli, His Tag)?

The catalog number for Recombinant Human Beta-2-Microglobulin/B2M Protein (E.coli, His Tag) is PKSH033260.

What sizes are available for Recombinant Human Beta-2-Microglobulin/B2M Protein (E.coli, His Tag)?

Recombinant Human Beta-2-Microglobulin/B2M Protein (E.coli, His Tag) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human Beta-2-Microglobulin/B2M Protein (E.coli, His Tag) come in?

Recombinant Human Beta-2-Microglobulin/B2M Protein (E.coli, His Tag) is available in 2 different pack sizes.

Is Recombinant Human Beta-2-Microglobulin/B2M Protein (E.coli, His Tag) in stock?

Recombinant Human Beta-2-Microglobulin/B2M Protein (E.coli, His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human Beta-2-Microglobulin/B2M Protein (E.coli, His Tag)?

Recombinant Human Beta-2-Microglobulin/B2M Protein (E.coli, His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human Beta-2-Microglobulin/B2M Protein (E.coli, His Tag)?

Estimated delivery time for Recombinant Human Beta-2-Microglobulin/B2M Protein (E.coli, His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human Beta-2-Microglobulin/B2M Protein (E.coli, His Tag)?

The safety data sheet for Recombinant Human Beta-2-Microglobulin/B2M Protein (E.coli, His Tag) is available here: https://789.bio/eb/LqTC4K.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

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