Recombinant Human DEFB104A Protein

Specifications

Catalog number

PKSH033265-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Defensins are cationic peptides. It is an important ingredient of the innate immune system. β-defensins are expressed on some leukocytes and epithelial surfaces. Four human β-Defensins have been identified to date: BD-1, BD-2, BD-3 and BD-4. β-defensins contain a six-cysteine motif, they forms three intra-molecular disulfide bonds. β-defensins are also chemoattractant towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors; they are released by proteolytic cleavage of a signal sequence.

Abbreviation

DEFB104A

Synonyms

BD-4; Beta-Defensin 104; Beta-Defensin 4; DEFB-4; DEFB104; DEFB104A; DEFB104B; DEFB4; Defensin Beta 104; hBD-4

UniProt

Q8WTQ1

Accession Number

Q8WTQ1

Expression System

E.coli

Tag

None

Sequence

Glu23-Pro72

Field of Research

Microbiology; immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

6.0 kDa

Observed Molecular Weight

9 kDa

Species

Human