Recombinant Human IFNA4 Protein (His Tag)

Specifications

Catalog number

PKSH033280-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. They are typically divided among three IFN classes: Type I, Type II and Type III. IFNA4 is a secreted protein and produced by macrophages. Two variants of IFNA4 (IFNA4a and IFNA4b) are known, which differ from each other by changes in their coding regions at nucleotide positions 220 and 410 .

Abbreviation

IFNA4

Synonyms

IFNA4; Interferon alpha-4; Interferon alpha-4B; Interferon alpha-76; Interferon alpha-M1

UniProt

P05014

Accession Number

P05014

Expression System

HEK293 Cells

Tag

C-His

Sequence

Cys24-Asp189

Field of Research

Cancer; immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

20.4 kDa

Observed Molecular Weight

20 kDa

Species

Human