Recombinant Human GMPR Protein (Human Cells, His Tag)

Specifications

Catalog number

PKSH033290-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

GMP Reductase 1 (GMPR) is a member of the IMPDH/GMPR family. GMPR exists as a homotetramer and catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase; nucleoside and nucleotide derivatives of G to A nucleotides; and in maintaining the intracellular balance of A and G nucleotides. GMP reductase gene expression may be regulated by MITF. At least two different alleles are known.

Abbreviation

GMPR

Synonyms

GMP Reductase 1; GMPR; GMPR1; Guanosine 5'-Monophosphate Oxidoreductase 1; Guanosine Monophosphate Reductase 1

UniProt

P36959

Accession Number

AAH08281.1

Expression System

HEK293 Cells

Tag

C-His

Sequence

Met 1-Ser345

Field of Research

Signal Transduction; Cell biology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

38.5 kDa

Observed Molecular Weight

40 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 40% Glycerol, 150mM NaCl, 1mM DTT, pH 8.0.

Species

Human