Recombinant Human PPIase/PPIL1 Protein (His Tag)

Specifications

Catalog number

PKSH033304-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Peptidyl-Prolyl Cis-Trans Isomerase-Like 1 (PPIase) belongs to the cyclophilin-type PPIase family. PPIases can accelerate the folding of proteins and catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIase is a ubiquitous protein and has highly expression in heart ; skeletal and muscle. PPIase contains a PPIase cyclophilin-type domain and four Cyclosporin A binding regions. PPIase might play an important role in proliferation of cancer cells through modulation of phosphorylation of stathmin. It is suggested that PPIase can act as as a novel molecular target for colon-cancer therapy.

Abbreviation

PPIase; PPIL1

Synonyms

CGI; UNQ; PRO; PPIL; CYPL; PPIase FKBP; Rotamase PPIL; FK506-Binding Protein; Peptidyl-Prolyl Cis-Trans Isomerase FKBP; Peptidyl-Prolyl Cis-Trans Isomerase-Like; PPIL1; CGI-124; CYPL1; PPIase; hCyPX;23 kDa FK506-Binding Protein;23 kDa FKBP; FK506-Binding Protein 7; FKBP23; FKBP-23; FKBP7; FKBP-7; Peptidyl-Prolyl Cis-Trans Isomerase FKBP7; Peptidyl-Prolyl Cis-Trans Isomerase-Like 1; PPIase FKBP7; Rotamase; Rotamase PPIL1; UNQ2425; PRO4984; peptidylprolyl isomerase like 1

UniProt

Q9Y3C6

Accession Number

Q9Y3C6

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Gly166

Field of Research

Signal Transduction; epigenetics and nuclear signal; immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

20.4 kDa

Observed Molecular Weight

19 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, pH 8.0.

Species

Human