Recombinant Human UBE2I/UBC9 Protein (GST Tag)

Specifications

Catalog number

PKSH033308-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

SUMO-Conjugating Enzyme UBC9 (UBC9) belongs to the ubiquitin-conjugating enzyme family. UBC9 is homologous to ubiquitin-conjugating enzymes (E2s) . However; instead of conjugating ubiquitin; UBC9 conjugates a ubiquitin homologue; Small Ubiquitin-Like Modifier 1 (SUMO-1) . The conjugation of ubiquitin requires the activities of ubiquitin-activating (E1) and conjugating (E2) enzymes. It is suggested that UBC9 might play a role in DNA repair and perhaps even in aging.

Abbreviation

UBE2I; UBC9

Synonyms

SUMO-Conjugating Enzyme UBC9; SUMO-Protein Ligase; UBC9; UBCE9; UBE2I; Ubiquitin Carrier Protein 9; Ubiquitin Carrier Protein I; Ubiquitin-Conjugating Enzyme E2 I; Ubiquitin-Protein Ligase I; p18

UniProt

P63279

Accession Number

P63279

Expression System

E.coli

Tag

N-GST

Sequence

Met 1-Ser158

Field of Research

Cell biology; epigenetics and nuclear signal; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

44.4 kDa

Observed Molecular Weight

40 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, pH 7.5.

Species

Human