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Product details

Recombinant Human Mesothelin/MSLN Protein (aa 296-598, His Tag)

Catalog number PKSH033310-01

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Price for PKSH033310-01

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Size / count 10 µg

Specifications

Catalog number
PKSH033310-01
Size / count
10 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
Mesothelin is a cell surface glycoprotein whose expression is limited to mesothelial cells of the serosa (pleura; pericardium; and peritoneum) and epithelial cells of the trachea; tonsils; fallopian tube; and kidneys. Mesothelin plays an important role in cell survival; proliferation; migration; invasion; tumor progression; and resistance to chemotherapy. The overexpression of mesothelin can activate NF-κB and signal transducer and activator of transcription 3 (Stat3) ; inhibit apoptotic signaling and TNF-α-induced apoptosis; and accelerate the G1–S transition. Mesothelin is also found overexpressed in various cancers; including malignant mesothelioma; pancreatic or ovarian carcinoma; sarcomas and in some gastrointestinal or pulmonary carcinomas. As a result of its limited expression in normal tissues; mesothelin has been reported as an ideal tumor-associated marker for the development of targeted therapy.
Abbreviation
Mesothelin; MSLN
Synonyms
CAK1; CAK1 antigen; MPF; MSLN; Megakaryocyte potentiating factor; Pre-pro-megakaryocyte-potentiating factor; SMR; mesothelin; soluble MPF mesothelin related protein
UniProt
Q13421
Accession Number
AAH09272.1
Expression System
HEK293 Cells
Tag
C-His
Sequence
Glu296-Ser598
Field of Research
Tags & Cell Markers, Cancer
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
34.9 kDa
Observed Molecular Weight
35-50 kDa
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human Mesothelin/MSLN Protein (aa 296-598, His Tag)?

The catalog number for Recombinant Human Mesothelin/MSLN Protein (aa 296-598, His Tag) is PKSH033310.

What sizes are available for Recombinant Human Mesothelin/MSLN Protein (aa 296-598, His Tag)?

Recombinant Human Mesothelin/MSLN Protein (aa 296-598, His Tag) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human Mesothelin/MSLN Protein (aa 296-598, His Tag) come in?

Recombinant Human Mesothelin/MSLN Protein (aa 296-598, His Tag) is available in 2 different pack sizes.

Is Recombinant Human Mesothelin/MSLN Protein (aa 296-598, His Tag) in stock?

Recombinant Human Mesothelin/MSLN Protein (aa 296-598, His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human Mesothelin/MSLN Protein (aa 296-598, His Tag)?

Recombinant Human Mesothelin/MSLN Protein (aa 296-598, His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human Mesothelin/MSLN Protein (aa 296-598, His Tag)?

Estimated delivery time for Recombinant Human Mesothelin/MSLN Protein (aa 296-598, His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human Mesothelin/MSLN Protein (aa 296-598, His Tag)?

The safety data sheet for Recombinant Human Mesothelin/MSLN Protein (aa 296-598, His Tag) is available here: https://789.bio/eb/XjLWfP.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

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