Recombinant Human C1QBP Protein (aa 74-282, His Tag)

Specifications

Catalog number

PKSH033350-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Complement Component 1Q Subcomponent-Binding Protein (C1QBP) is a nucleus protein that belongs to the MAM33 family. C1QBP is known to bind to the globular heads of C1q molecules and inhibit C1 activation. Mitochondrial C1QBP is a critical mediator of p14ARF-induced apoptosis. C1QBP functions as a chemotactic factor for immature dendritic cells, and migration is mediated through ligation of both C1QBP and cC1qR/CR. C1QBP overexpression successfully blocks mRNA accumulation from the adenovirus major late transcription unit (MLTU) and stimulates RNA polymerase II carboxy-terminal domain phosphorylation in virus-infected cells.

Abbreviation

C1QBP

Synonyms

ASF/SF2-Associated Protein p32; C1QBP; C1qBP; Complement Component 1 Q Subcomponent-Binding Protein Mitochondrial; GC1QBP; Glycoprotein gC1qBP; HABP1; Hyaluronan-Binding Protein 1; Mitochondrial Matrix Protein p32; SF2P32; gC1q-R Protein; gC1qR; p33

Accession Number

Q07021

Expression System

E.coli

Tag

C-His

Sequence

Leu74-Gln282

Field of Research

Microbiology; immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

24.9 kDa

Observed Molecular Weight

34 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 20% Glycerol, 1mM DTT, pH 7.5.

Species

Human