Recombinant Human FCRL1 Protein (His Tag)

Specifications

Catalog number

PKSH033364-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Fc Receptor-Like Protein 1 (FCRL1) is a single-pass type I membrane protein that may function as an activating coreceptor in B cells. FCRL1 is primarily expressed in secondary lymphoid tissues by mature subsets of B cells. It can be detected in the spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. It is specifically expressed by mature B lineage cells with higher expression at the protein level in naive B cells compared to memory B cells. FCRL1 contains three extracellular C2-like immunoglobulin domains, a transmembrane domain, and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs and may play a role in the regulation of cancer cell growth.

Abbreviation

FCRL1

Synonyms

CD307a; FCRH1; FCRL1; Fc Receptor Homolog 1; Fc Receptor-Like Protein 1; FcR-Like Protein 1; FcRH1; FcRL1; IFGP Family Protein 1; IFGP1; IRTA5; Immune Receptor Translocation-Associated Protein 5; hIFGP1

UniProt

Q96LA6

Accession Number

Q96LA6

Expression System

HEK293 Cells

Tag

C-His

Sequence

Ala17-Asn303

Field of Research

Immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

32.2 kDa

Observed Molecular Weight

39-50 kDa

Species

Human