Recombinant Human IFNGR1 Protein (His Tag)

Specifications

Catalog number

PKSH033429-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Interferon gamma receptor 1 (IFNGR1) encoded by the IFNGR1 gene, is a single-pass type 1 membrane protein which belongs to the type II cytokine receptor family. IFNGR1 is phosphorylated at Ser/Thr residues after translation. IFNGR1 is a receptor for interferon gamma, two receptors bind one interferon gama dimer. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.

Abbreviation

IFNGR1

Synonyms

CD119; IFNGR; IFNGR1; IMD27A; IMD27B; Interferon gamma receptor 1

UniProt

P15260

Accession Number

P15260

Expression System

HEK293 Cells

Tag

C-His

Sequence

Glu18-Ser245

Field of Research

Microbiology; immunology; Stem cells

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

26.8 kDa

Observed Molecular Weight

40-50 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Species

Human