Recombinant Human Cathepsin Z Protein (His Tag)

Specifications

Catalog number

PKSH033443-01

Size / count

10 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Cathepsin Z is a lysosomal cysteine proteinase and belongs to the peptidase C1 family. Human Cathepsin Z contains a singnal sequence; a propeptide and a mature chain. It exhibits bothcarboxy-monopeptidase and carboxy-dipeptidase activities. In contrast to cathepsin B; it does not act as an endopeptidase. Cathepsin Z is restricted to the cells of theimmune system; predominantly monocytes; macrophages and dendritic cells. It is expressed ubiquitously in cancer cell lines and primary tumors. Like other members of this family; Cathepsin Z may be involved in tumorigenesis.

Abbreviation

Cathepsin Z

Synonyms

CTSZ; Cathepsin P; Cathepsin X; Cathepsin Z

UniProt

Q9UBR2

Accession Number

Q9UBR2

Expression System

HEK293 Cells

Tag

C-His

Sequence

Gly24-Val303

Field of Research

Tags & Cell Markers

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

32.5 kDa

Observed Molecular Weight

37-40 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 4mM HCl.

Species

Human