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Product details

Recombinant Human IL1R2/CD121b Protein (His Tag)

Catalog number PKSH033449-01

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Price for PKSH033449-01

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Size / count 10 µg

Specifications

Catalog number
PKSH033449-01
Size / count
10 µg
Dry ice
No
Hazardous
No
Discontinued
No
Background
Interleukin-1 receptor type 2 (IL1R2) belongs to the interleukin-1 receptor family. Two distinct types of IL1 receptors which are able to bind IL1 specifically have been identified; designated as IL1RI (IL1RA) and IL1RII (IL1RB) . IL1 receptor type II is a 68 kDa transmembrane protein found on B lymphocytes; neutrophils; monocytes; large granular leukocytes and endothelial cells. IL1R2 is non-signaling receptor forIL1A; IL1B and IL1RN; reduces IL1B activities. IL1R2 serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. IL1R2 modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
Abbreviation
IL1R2; CD121b
Synonyms
IL1R; Interleukin-1 receptor type; IL-1R; IL1R2; CD121b; CDw121b; IL-1R-2; IL-1RT-2; IL-1RT2; IL1R2c; IL1RB; CD121 antigen-like family member B; IL-1 type II receptor; IL-1R-beta; Interleukin-1 receptor beta; Interleukin-1 receptor type 2; Interleukin-1 receptor type I; IL-1R type II; IL-1RII
Accession Number
P27930
Expression System
HEK293 Cells
Tag
C-His
Sequence
Phe14-Glu343
Field of Research
Cardiovascular; immunology; Stem cells
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
38.6 kDa
Observed Molecular Weight
50 kDa
Species
Human

Frequently Asked Questions

What is the catalog number for Recombinant Human IL1R2/CD121b Protein (His Tag)?

The catalog number for Recombinant Human IL1R2/CD121b Protein (His Tag) is PKSH033449.

What sizes are available for Recombinant Human IL1R2/CD121b Protein (His Tag)?

Recombinant Human IL1R2/CD121b Protein (His Tag) is available in the following size(s): 10 µg, 50 µg.

How many pack sizes does Recombinant Human IL1R2/CD121b Protein (His Tag) come in?

Recombinant Human IL1R2/CD121b Protein (His Tag) is available in 2 different pack sizes.

Is Recombinant Human IL1R2/CD121b Protein (His Tag) in stock?

Recombinant Human IL1R2/CD121b Protein (His Tag) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Human IL1R2/CD121b Protein (His Tag)?

Recombinant Human IL1R2/CD121b Protein (His Tag) is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Human IL1R2/CD121b Protein (His Tag)?

Estimated delivery time for Recombinant Human IL1R2/CD121b Protein (His Tag) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Human IL1R2/CD121b Protein (His Tag)?

The safety data sheet for Recombinant Human IL1R2/CD121b Protein (His Tag) is available here: https://789.bio/eb/qjTC88.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

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